General Investigation

We hope that the recommendations will be widely disseminated and will be approved by editors of leading biomedical magazines, as well as that in their further work on updating and improving the participation of all stakeholders. 1. The structure of the research process and their approval by the ethics committee General Investigation must be actual, reasonable and well-planned, the structure of the study should meet its objectives and be approved by the ethics committee. Failure to comply may lead to unfair practice, research and publications. Practical steps 1.

Laboratory and clinical tests must be performed according to protocol, a preliminary study – according to a written plan. 2. The protocol should help find answers to specific questions, not only to collect data. 3. The protocol should be studied in detail and approved by all parties involved in the investigation, possibly including the participants (patients). 4. Final text of the protocol should be included in the study report.

5. It is desirable to study the early stages of an agreement on the functions of all researchers and resolve issues related to authorship and publishing. 6. At the planning stage should provide all the statistical aspects of research, including an evaluation of the statistical power to sample was not too small or excessively large. 7. Before any research involving human subjects, and and research involving work with the histories and tissues of the human body, should receive formal written permission of the Ethics Committee, which was formed in accordance with generally accepted principles.